AIDS Special

Various Artists...

Das Produkt Various Artists - Live Aid [4 DVDs] finden Sie ab 93,95 EUR bei Amazon. Live Aid (4 Dvd) ...

Direkt zum Angebot »


Atazanavir

Atazanavir.eu :: service, offers and products on the Internet


Atazanavir is a drug which is used in oral dosage forms for the therapy of HIV infection and is counted to the group of protease inhibitors. Approval by the FDA in June 2003 by the European Commission in March 2004. License holder is the pharmaceutical company Bristol-Myers Squibb.

Trade name:
Reyataz ®
Indications and efficacy
Atazanavir is approved for the treatment of HIV infection in adults. Be combined in comparison to earlier representatives of the same class of drugs atazanavir should advantageously be fed only once daily, and may in the course of highly active antiretroviral therapy (HAART) with drugs from the group of transcriptase inhibitors (NRTIs).

The efficacy was compared with other protease inhibitors (nelfinavir and lopinavir / ritonavir) and efavirenz compared with the involved clinical trials showed an approximately similar potency.
Pharmacokinetics
When atazanavir ranges, in contrast to other protease inhibitors, from a single dose per day to achieve effective plasma levels. Concomitant food intake does not affect the bioavailability may reduce positive during concomitant use of certain drugs absorption. In the blood are 86% of the active ingredient found in protein-bound form. The metabolism takes place primarily in the liver by cytochrome P450-dependent monooxygenases. Elimination occurs with a mean plasma half-life of about 7 hours.
Mechanism of Action
Atazanavir is a so-called protease inhibitor and engages as such a mechanism in the reproduction of HIV. Atazanavir binds to the viral protease enzyme and thus inhibits its function. Infected cells are no longer able to reproduce functional viruses, the viral load decreases.

Atazanavir is similar to lopinavir with a second protease inhibitor in combination. It has the function, the reduction of atazanavir in the liver to slow down and make it the active ingredient over time the organism is available.
Side effects and interactions
Overall, the tolerability of atazanavir over other representatives of the protease inhibitors will be better assessed. Disorders of the gastrointestinal tract, such as abdominal pain, nausea and diarrhea, and disorders of lipid metabolism (hyperlipidemia and lipodystrophy), and elevated cholesterol levels are less frequently observed in therapy with atazanavir as compared with the above mentioned substances. However, lead increased bilirubin in the blood and, subsequently, jaundice occasionally require discontinuation of therapy.

As with other protease inhibitors atazanavir arises in connection with the problem of interaction with other drugs that are metabolised by the cytochrome P450 isoenzyme CYP3A4 reduced. This results in a number of contraindications. Some drugs such as midazolam, occupational toxins or the neuroleptic pimozide should not be used in patients treated with atazanavir or other protease inhibitors. Also, concomitant administration of atazanavir with efavirenz, stavudine, didanosine, or atazanavir, clarithromycin results in changes in plasma levels.

Exklusive Gesundheits-Domains stehen zum Verkauf

Das Wichtigste im Leben ist die Gesundheit!

Und gute Internetadressen sind sehr wichtig für einen guten Internet-Auftritt.


Diese Domains verleihen dem Webseitenauftritt Glaubwürdigkeit und Autorität.

Hier finden Sie eine Aufstellung von TOP GESUNDHEITS-DOMAINS die Sie kaufen können.

Eine Top Gesundheits-Domain ist ein hervorragender und vor allem einzigartiger Wettbewerbsvorteil gegenüber Ihrer Konkurrenz und wird Ihnen viele Werbekostenersparnisse bringen.

Außerdem ist so eine Gesundheitsdomain sehr leich zu merken, prägnant und somit weniger Tippfehler anfällig.

Diese Top Gesundheits-Domains eignen sich für Native Advertising, Werbekapagnen und Storytelling. Machen Sie Ihr Unternehmen und Ihre Website zu einem führenden Einkaufsportal im Gesundheitsbereich.

Treffen Sie jetzt die richtige Kaufentscheidung für eine Gesundheits-Domain uns genießen Sie Ihre Vorteile durch Imagegewinn.

Für weitere Informationen Klicken Sie bitte auf die Domain Ihrer Wahl.

Ohne Socke kein...

...

mehr Infos »

aidskranke.de » Blog...

...

mehr Infos »

Best Print Biz.com...

...

mehr Infos »

Developing country ownership...

...

mehr Infos »

AIDS Activists Part...

...

mehr Infos »

Sonocaddie V300 Plus...

...

mehr Infos »

Torna il premio...

...

mehr Infos »

Aids in Afrika...

...

mehr Infos »

Figuring Out AndVerifying...

...

mehr Infos »

Neuartige Aids-Viren im...

...

mehr Infos »

The Other Side...

...

mehr Infos »





Berührendes Drama um...

...

mehr Infos »

Hormonelle Verhütungsspritzen erhöhen...

...

mehr Infos »

North Coast Medical...

...

mehr Infos »

Seduced by the...

...

mehr Infos »

Aids-Hilfe: Kriminalisierung schadet...

...

mehr Infos »

„Deadline“ stellt Aids-Problematik...

...

mehr Infos »

Dear band aids...

...

mehr Infos »